Homologous Recombination Deficiency Solution
What is HRD and why is it important?
Homologous recombination deficiency (HRD) is caused by cells’ inability to repair double-stranded DNA breaks with homologous recombination repair (HRR), causing mutations that lead to development of certain cancers. Germline and somatic molecular testing allow the detection of HRR mutations that cause HRD and the accumulated genomic damage that result from them. However, over the last decade, HRD has become the new gold standard to help inform cancer care strategies.
Current challenges with HRD detection offerings
- Data not owned by the lab
- Weak solution support