SOPHiA DDM™ for
Agilent SureSelect™
Human All Exon V8

Delivering greater insights through comprehensive solutions

The SOPHiA DDM™ for Agilent SureSelect™ Human V8 enables comprehensive genomic investigation, using the latest reference data, for maximum discovery power. This FASTQ-to-report analytical workflow is designed to empower and accelerate the assessment and identification of variants associated with rare and inherited disorders.

Hg38-based analytics delivering the most up-to-date results for research insights

Efficient 35.1 Mb target space spanning the entire human exome

Covers protein coding regions from RefSeq, CCDS, and GENCODE (as well as the TERT promoter)

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Product Details

The SOPHiA DDM™ Experience:

  • New pipeline, same platform: SOPHiA DDM™ data solutions empower researchers to make the most out of their NGS data, enhancing and improving potential care for the 400M+ global individuals affected by inherited & rare disorders.
  • Unify your workflow: analyze, interpret and report all within SOPHiA DDM™
  • Comprehensive, sensitive detection: identify SNVs & Indels with confidence
    • Sensitivity: 99.3%-99.48%*
    • Precision: 98.3-98.7%*
  • Leverage the newest and most trusted databases: OMIM, HPO and more
  • Visualize & understand: use intuitive, dedicated tertiary features to filter your investigation of disorder-causing variants
  • Community resources: access shared, anonymized data from other SOPHiA DDM™ users to compare results and gain stronger insights into variants of interest
The SOPHiA DDM™ for Agilent SureSelect™ Human V8 Screenshot
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Specifications

Attribute Content
Diseases Covered Rare and inherited disorders
Genes Protein coding regions from RefSeq, CCDS, and Gencode (as well as the TERT promoter)
Target Region Size 35.1 Mb / 22,202 genes
Sample Type Blood
DNA Input Amount 50 – 200 ng
Sequencer Compatibility
  • Illumina™ NextSeq 550
  • Illumina™ NovaSeq
Analysis Time From FASTQ Overnight
Detected Variants
  • SNVs
  • Indels
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Footnotes

*Range of % refers to the different comparisons of SureSelect™ Human All Exon v8 with common regions of other Exome panels. Data on file.