We are thrilled to announce our participation in the ESMO Asia Congress 2024!

Join the SOPHiA GENETICS team at booth #E406 and explore how we are driving groundbreaking innovations in cancer research and treatment.

From our collaboration with Memorial Sloan Kettering cancer Center to decentralize MSK-ACCESS and MSK-IMPACT, to our launch of SOPHiA DDM™ Residual Acute Myeloid (RAM) Solution, we are committed to supporting clinical researchers with variant detection and analysis, biomarker discovery, and therapy selection.

We look forward to connecting with you at ESMO Asia 2024!

SOPHiA GENETICS™ is excited to be for the first time part of the BioJapan Congress. You will have the chance to chat with our team at booth to discuss our solutions and our universal SOPHiA DDM™ Platform.

Asia‘s Premier Hybrid Partnering Event

Oct 9 Wed - 11 Fri. 2024| PACIFICO Yokohama

The diagnostics company has implemented the SOPHiA DDM™ Platform to enhance its solid tumor testing 

Boston, MA and Rolle, Switzerland, July 4, 2024 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native healthcare technology company and a global leader in data-driven medicine, today announced that Dhiti Omics Technologies, a precision molecular diagnostics service provider in India, is live on the SOPHiA DDM™ Platform. The company will use SOPHiA GENETICS’ technology to enhance its solid tumor testing capabilities.

Dhiti Omics specializes in molecular diagnostic and genetic testing. By implementing SOPHiA DDM™ for the Agilent SureSelect Cancer CGP application, Dhiti Omics will improve its ability to provide researchers actionable information on mutations and biomarkers across hundreds of genes.

“Our team at Dhiti Omics is passionate about furthering the use of precision medicine and ensuring people in India and throughout the world have access to testing for better health outcomes,” said Sudha N. Rao, Ph.D., Founder and Director of Dhiti Omics Technologies. “Combining high-quality reagents, and powerful analytics into one unique workflow will help us maximize insights from comprehensive genomic profiling data. This will ensure we’re delivering the fastest and most accurate diagnostics to our customer base.”

SOPHiA DDM™ for SureSelect CGP application combines Agilent’s best-in-class genomic profiling assay kit with the SOPHiA DDM™ Platform. Launched in 2023, SureSelect Cancer CGP application offers comprehensive genomic profiling. With the SOPHiA DDM™ AI Platform, Dhiti Omics will have an integrated solution for rapid and accurate insights on the basis of the latest guidelines reflecting relevant biomarkers.

“Our Platform and applications are designed to enable companies like Dhiti Omics to more easily advance precision medicine,” said Ricardo Mendonca Filho, Ph.D., Managing Director, LAPAC, SOPHiA GENETICS. “By using SOPHiA DDM™, Dhiti Omics can ensure speed and accuracy of solid tumor testing to best support the Indian population.”

The combined efforts of Agilent and SOPHiA GENETICS make it possible for companies like Dhiti Omics to facilitate novel approaches to cancer research and diagnostics.

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on LinkedIn.

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native healthcare technology company on a mission to expand access to data-driven medicine by using AI to deliver world-class care to patients with cancer and rare disorders across the globe. It is the creator of the SOPHiA DDM™ Platform, which analyzes complex genomic and multimodal data and generates real-time, actionable insights for a broad global network of hospital, laboratory, and biopharma institutions.  For more information, visit SOPHiAGENETICS.COM and connect with us on LinkedIn.

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence. 

SOPHiA GENETICS Forward-Looking Statements: 
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Media Contact:
Kelly Katapodis
[email protected] 

SOPHiA GENETICS technology helps advance cancer research across India

SOPHiA GENETICS and Karkinos Healthcare join forces to propel cutting-edge genomic solutions for breakthroughs in personalized cancer care in India

Boston, MA and Rolle, Switzerland, January 15, 2024 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that Karkinos Healthcare, a purpose-driven cancer care technology network based in India, will partner with SOPHiA GENETICS and adopt the SOPHiA DDM™ Platform to advance cancer testing and research for blood cancers and solid tumors to underserved areas in low and middle-income countries.

Karkinos Healthcare is a purpose-driven, technology-led oncology platform, focused on early detection, advanced diagnostics, and treatment delivery of common cancers, using its Distributed Cancer Care Network across India. Karkinos Healthcare provides end-to-end solutions for oncology ecosystem, including disease screening, diagnosis, surgery, chemotherapy, radiotherapy and comprehensive patient navigation through the care continuum, in addition to operating advanced research and development laboratories. The company is on a mission to create ‘Community as a Cancer Centre’ with an endeavour to serve one million patients annually by addressing the accessibility and affordability gaps in cancer care through a digitally curated hub and spoke and further spoke model, and not restrict cancer care to comprehensive centres alone.

“It is our continued goal to improve health outcomes for patients globally by expanding access to precision oncology and equipping local health institutions with the tools and technology needed to practice data-driven medicine,” said Dr. Jurgi Camblong, CEO and Co-founder, SOPHiA GENETICS. “By aligning with Karkinos, who share the mutual goal, we can help increase the use of best-in-class cancer testing for rural and underserved communities around the world.”

On this strategic partnership, Dr. R Venkataramanan, Founder and CEO, Karkinos Healthcare said, “Through collaborative research initiatives, Karkinos Healthcare aims to address the comprehensive genomic landscape identification for Indian population, with a focus on precision medicine. This alliance will have the potential to generate evidence and world-class research for faster and accurate diagnosis and better control and management of cancers, particularly for the underprivileged population of our country.”

The SOPHiA DDM™ Platform is designed to compute a wide array of genomic variants and continually hone machine learning algorithms to detect rare and challenging cases. Karkinos Healthcare will use SOPHiA GENETICS’ technology to expand its offerings, advance research and streamline workflow for a variety of blood cancers, including Myeloid cancer and Lymphoma. In addition, the company will analyse solid tumours for a variety of cancer types including ovarian, prostate, breast, pancreas, lung, colorectal, skin, and brain cancers.

The SOPHiA DDM™ Platform offers tailored NGS-based workflows to streamline processes – from sample to report – to accelerate analysis. By using the SOPHiA DDM™ Platform, researchers from Karkinos Healthcare will quickly obtain high-quality and reproducible data that will ultimately accelerate clinical research studies and advance the use of precision medicine.

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn,Facebook, and Instagram. Where others see data, we see answers. 

Product Disclaimer

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures, unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.

SOPHiA GENETICS: Forward-Looking Statement

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

About Karkinos Healthcare

Karkinos Healthcare is a purpose driven technology-led oncology health care platform for early detection and diagnosis of common cancers. The organisation espouses use of a distributed cancer care network, while working with a network of healthcare institutions and domain experts within the ecosystem, with an aim to provide comprehensive cancer care closer to individuals’ homes.

Tata Group, Reliance Industries, Mayo Clinic, and Rakuten Medical Inc. are among the World’s leading organizations that have invested in Karkinos Healthcare. The company has also partnered with Tata Memorial Hospital, Guys and St Thomas NHS Foundation Trust (UK), and has inked several research collaborations with leading academic institutions in the United States to stay on the cutting edge of oncology treatment and care. 

To learn more, visit https://www.karkinos.in/about-us/

Media Contacts:

Kelly Katapodis
[email protected] 

Team Corporate Communications
[email protected]

The hospital will use the SOPHiA DDM™ Platform to further its work with myeloid disorders and advance the development of precision medicine

BOSTON and Rolle, Switzerland, September 29, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that Shaare Zedek, the largest multi-disciplinary medical center in Jerusalem, is now live on the SOPHiA DDM™ Platform. The Platform will enable Shaare Zedek to advance its insights the treatment of myeloid disorders and further develop the application of precision medicine. 

Myeloid disorders affect millions of people worldwide, and while there are various types and classification of these disorders, collectively all myeloid disorders originate from hematopoietic disruptions in the myeloid lineage. Because of the wide range of disorders and the complexity of these genetic mutations, treatment and therapy techniques evolve rapidly and are highly dependent on timely, cost-effective, and reliable sequencing strategies.

Shaare Zedek Medical Center has been providing top-level medical research and care for the people of Jerusalem since 1902. Today the hospital’s name has become synonymous with advanced medicine, compassionate care, and many of the brightest medical minds in Israel. The use of SOPHiA GENETICS technology will allow Shaare Zedek to continue leading the way in Israel with cutting-edge technology aligned with the latest guidelines from the European Hematology Association (EHA). 

“The last several years have shown rapid progress in targeted therapies for myeloid disorders,” said Kevin Puylaert, Managing Director, EMEA, SOPHiA GENETICS. “With that progress has come an increase in international recommendations that can be challenging to keep up with. The implementation of the SOPHiA DDM™ Platform by Shaare Zedek will allow the hospital to keep pace with the progress while advancing its research to best serve its community.”

Molecular profiling via next-generation sequencing (NGS) is widely used to investigate the pathogenic variants causing different myeloid malignancies. However, NGS produces a vast amount of complex data. The SOPHiA DDM™ Platform is an NGS-based application that uses artificial intelligence (AI) to efficiently analyze and interpret raw NGS data for researchers. The Platform provides streamlined insights in a matter of days, enabling clinical researchers to make data-driven recommendations more quickly. 

In addition to quickly providing analysis and insights, the SOPHiA DDM™ Platform makes it easier for researchers to obtain reproducible data that can help to accelerate their studies. With the SOPHiA DDM™ Platform, Shaare Zedek Medical Center will retain complete ownership of its database, supporting the research team as it continues to increase its expertise.

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on X (formerly known as Twitter), LinkedIn, Facebook, and Instagram. 

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X (formerly known as Twitter), LinkedIn, Facebook, and Instagram. Where others see data, we see answers. 

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.

SOPHiA GENETICS Forward-Looking Statements: 

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Media Contact:
Kelly Katapodis
[email protected] 

New HRD test uses SOPHiA DDM™ Platform to increase accuracy in HRD detection

BOSTON and Rolle, Switzerland, July 19, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company in the healthcare space and a leader in data-driven medicine, today announced that the Taiwanese genomics lab SOFIVA GENOMICS has introduced a new product using SOPHiA GENETICS technology. The product is a new homologous recombination deficiency (HRD) test – the SOFIVA GENOMICS HRD Status Test – that leverages the SOPHiA DDM™ Platform to increase accuracy in HRD detection.

HRD is caused by a cell’s impaired ability to repair DNA double-stranded breaks through the homologous recombination repair (HRR) pathway and is linked with the development of certain cancers, including advanced ovarian cancer, which is one of the top 10 causes of death for women in Taiwan. For those diagnosed with ovarian cancer, HRD has been shown to be a potential predictive biomarker for therapy response.

SOFIVA GENOMICS has long been devoted to the research and development of cancer-based precision medicine and the SOFIVA GENOMICS HRD Test is its latest breakthrough. With the SOPHiA DDM™ Platform, the SOFIVA GENOMICS HRD Test is expected to provide a fast and highly accurate assessment of HRD-positive tumors, helping to support decision-making. 

"Our collaboration with SOPHiA Genetics is deeply advantageous for refining and localizing precision medicine in Taiwan. SOPHiA GENETICS provides a framework for localizing HRD testing in Taiwan, allowing us to retain genetic data needed to perfect the robustness and accuracy of HRD testing services and help even more patients identify suitable treatment," shares SOFIVA GENOMICS’ general manager, Chia-Cheng Hung.

Testing for HRD can produce a complex data set that is time-intensive and costly to analyze. The SOPHiA DDM™ Platform uses artificial intelligence and machine learning with patented technologies to analyze raw next-generation sequencing (NGS) data, streamlining it for simplified interpretation, and expedited reporting. 

“The SOFIVA GENOMICS HRD Test uses the strengths of the SOPHiA DDM™ Platform to provide highly accurate testing that aids clinical researchers in making data-driven decisions,” said Ricardo Mendonca Filho, PhD, Managing Director, LAPAC, SOPHiA GENETICS. “We are proud to work with SOFIVA GENOMICS and support their efforts to advance precision medicine in their market, making it more accessible to their population.”

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn,Facebook, and Instagram.

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn, Facebook, and Instagram. Where others see data, we see answers. 

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.

SOPHiA GENETICS Forward-Looking Statements: 

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Media Contact:
Kelly Katapodis
[email protected] 

SOPHiA GENETICS technology to aid research associated with hereditary cancers and disorders

BOSTON and LAUSANNE, Switzerland, June 22, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company in the healthcare space and a leader in data-driven medicine, today announced that Ankara Etlik City Hospital, the largest hospital in the capital city of Turkey, is live on the SOPHiA DDM™ Platform. The hospital, which opened its doors in September 2022 and serves roughly 15,000 patients daily, will utilize multiple SOPHiA GENETICS solutions to streamline genomic testing, specifically associated with hereditary disorders.

“Since opening our doors eight months ago, we’ve seen more than two million patients,” said Dr. Taha Bahsi, Head of Medical Genetics, Ankara Etlik City Hospital. “We are investing in technologies like SOPHiA DDM™ to best serve our community. The SOPHiA GENETICS technology will help create efficiencies in the analysis of genomic profiles and the identification of variants often associated with hereditary disorders such as cancers.“

Hereditary cancer is responsible for roughly one in 10 diagnosed cancers. Next-generation sequencing (NGS), is commonly used in the detection of biomarkers for hereditary cancers but produces a vast and complex data set that is timely for researchers to analyze. Using an array of sophisticated algorithms, the SOPHiA DDM™ Platform helps to streamline and expedite data analysis, which will save valuable time for clinical researchers. In addition, the tailored NGS-based workflows empower researchers to obtain high-quality, reproducible data that helps accelerate cancer research, including testing for new and existing therapies. 

“The SOPHiA DDM™ Platform offers multiple applications paired with sophisticated algorithms that allow organizations such as Ankara Etlik City Hospital to increase the volume of research and testing,” said Abhimanyu Verma, Chief Technology Officer, SOPHiA GENETICS. “Our platform connects data points from institutions globally, allowing Ankara Etlik City Hospital’s researchers to expedite the analysis of genomic profiles and draw further insights that their teams can leverage to better care for the millions of people in and around the capital city of Ankara..”

Ankara Etlik City Hospital has implemented SOPHiA DDM™ applications that will create a streamlined workflow to help accelerate research and will enable Ankara Etlik City Hospital to develop an in-house database of genomic data and insights. This database will help to create efficiencies with research and support experts as they work to make data-driven decisions. 

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on Twitter,  LinkedIn,  Facebook, and Instagram. 

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn, Facebook, and Instagram.

 Where others see data, we see answers. 

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.

SOPHiA GENETICS Forward-Looking Statements: 

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Media Contact:
Kelly Katapodis
[email protected] 

SOPHiA DDM™ HRD Solution will help empower clinical researchers to advance cancer research  

BOSTON and LAUSANNE, Switzerland, April 4, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company in the healthcare space and a leader in data-driven medicine, today announced that Tel Aviv Sourasky Medical Center (Ichilov), the largest acute care facility in Israel, has chosen to use SOPHiA DDM™ to enhance its genetic testing capabilities. The facility, which serves a population of one million people, will use the SOPHiA DDM™ Homologous Recombination Deficiency (HRD) Solution to help advance its clinical oncology research.

HRD is caused by a cell’s impaired ability to repair DNA double-stranded breaks through the homologous recombination repair (HRR) pathway and is a common feature of high-grade serous ovarian cancer (HGSOC) as well as breast, prostate, and pancreatic cancers. For those diagnosed with these cancer types, HRD can be used as a potential predictive biomarker for therapy response.

The SOPHiA DDM™ HRD Solution provides a unique approach to molecular cancer testing by combining the identification of HRD-causing mutations with the analysis of HRD-induced genomic instability across the whole genome of tumor samples. By implementing SOPHiA DDM™ HRD Solution, Tel Aviv Sourasky Medical Center (Ichilov) will have the opportunity to identify larger populations of individuals with HRD-positive cancer who may benefit from treatment with PARP inhibitors (PARPi).

“The implementation of methods able to detect HRD is crucial for identifying patients who could benefit from treatment with PARPi,” said Dr. Ariel Erental, Tel Aviv Sourasky Medical Center. “The SOPHiA DDM™ HRD Solution will help to inform data-driven decisions that advance the clinical research at Tel Aviv Sourasky Medical Center into HRD-associated cancers.”

SOPHiA DDM™ HRD Solution enables laboratories and healthcare institutions to identify HRR mutations and measure genomic instability via a decentralized approach. This approach to HRD testing for tumor samples allows the users to retain full ownership of their data, saving time and expense, while offering comprehensive genomic insights powered by deep learning algorithms.

“SOPHiA GENETICS is working to make data-driven medicine more broadly accessible to patients around the globe,” said Ken Freedman, Chief Revenue Officer, SOPHiA GENETICS. “By implementing SOPHiA DDM™ HRD Solution, Tel Aviv Sourasky Medical Center will have access to high analytical performance and streamlined bioinformatics workflows, making it more efficient to detect HRD status in advanced ovarian cancer and other relevant cancers.” 

In addition to supporting Tel Aviv Sourasky Medical Center in its work to detect HRD status in select cancers,  the powerful analytics of SOPHiA DDM™ HRD Solution will help the Medical Center maximize in-house genomic insights to help advance its clinical research capabilities.

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn, Facebook, and Instagram. 

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn, Facebook, and Instagram. Where others see data, we see answers. 

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.

SOPHiA GENETICS Forward-Looking Statements:

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Media Contact: 
Nick Puleo
[email protected] 

BOSTON, Mass, United States, LAUSANNE, Switzerland, and TAIPEI CITY, Taiwan – March 9, 2022 – SOPHiA GENETICS (Nasdaq: SOPH) today announced that SOFIVA GENOMICS, which is one of the largest genetic testing companies in Taiwan aiming to provide genetic testing to clinicians, is the first institution in Asia Pacific to adopt SOPHiA GENETICS’ technology to support HRD testing. SOFIVA GENOMICS has been deeply involved in the field of clinical medicine and cancer monitoring for many years and found great success while implementing the solution for advanced HRD (Homologous Recombination Deficiency) detection using deep learning with the SOPHiA DDMPlatform. 

SOFIVA GENOMICS has compared the SOPHiA DDM HRD Solution with alternative solutions on hundreds of ovarian cancer samples and has concluded that SOPHiA GENETICS offered analysis technology to simultaneously detect more HRR (Homologous Recombination Repair) genes, including BRCA 1 and BRCA 2. They evaluated the integrity of the genome to comprehensively detect the HRD status of patients to determine whether they are suitable for treatment with precision therapy.

HRD is a complex biomarker, important for PARP inhibitors that help identify whether cancer patients may respond better to specific treatments. It is found in more than half of all cases of high-grade serous ovarian cancer (HGSOC), which accounts for about 70-80% of all deaths related to ovarian cancer. Its use could ultimately lead to personalized therapies that benefit the 150,000 patients with ovarian cancer on average per year in Asia Pacific.

While many labs are adopting HRD solutions, having to send samples out for analysis can get expensive and increase time between reporting. The SOPHiA DDM Platform offers a unique technology for detecting HRD with novel deep-learning algorithms. In addition, the platform helps users enhance their research with advanced filtering options to discover more actionable insights from the raw data with more elaborate reporting capabilities.

“Our collaboration with SOPHiA GENETICS will strengthen the promotion of SOFIVA precision medicine in Taiwan, locally,” said Dr. Double Hong, General Manager of SOFIVA GENOMICS.  “SOPHiA GENETICS offers an in-house HRD solution and allows us to keep our data ownership. We can together provide the most comprehensive and accurate HRD testing services in Taiwan.”

“It’s great to see SOFIVA’s positive and rapid response to the early implementations of our SOPHiA DDM HRD Solution. Our goal has always been to propel the capabilities of cancer research further. We anticipate many more clinical institutions will adopt our SOPHiA DDM platform technology to support HRD testing in the near future and very much look forward to indirectly supporting their patients,” said Jurgi Camblong, co-founder and CEO of SOPHiA GENETICS.

About SOFIVA GENOMICS:

SOFIVA GENOMICS is one of the largest genetic testing companies in Taiwan, accredited by LDTS, TAF, and certified by CAP and Illumina.  Starting from maternal fetal medicine (MFM), including reproductive, prenatal, and neonatal genetic testing, SOFIVA GENOMICS has expanded the scope of its services to precision medicine, including cancer genetic screening, targeted therapy, and monitoring recurrence or relapse. SOFIVA GENOMICS provides one-stop genetic testing service in maternal fetal medicine and precision medicine.

About SOPHiA GENETICS

SOPHiA GENETICS (Nasdaq: SOPH) is a healthcare technology company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-based SaaS platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by more than 790 hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn and Instagram. Where others see data, we see answers. 

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures, unless specified otherwise. The information included in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.

SOPHiA GENETICS Forward-Looking Statements:

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this document speak only as of the date of this press release. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Media Contact:
Eliza Bamonti
[email protected]

BOSTON, United States, LAUSANNE, Switzerland, and HIROSHIMA, Japan – February 22, 2022 – SOPHiA GENETICS (Nasdaq: SOPH), today announced an agreement with Hiroshima University, one of the top public universities in Hiroshima City, Japan, to support their molecular profiling by next-generation sequencing (NGS) in investigating the pathogenic variants causing different blood cancer disorders.

Hiroshima University is home to one of the largest university research institutes in the field of radiation biomedical science in Japan. With NGS for myeloid testing not widely available in Japan, a group of Hiroshima University researchers tapped the SOPHiA DDM Platform to assist with the clinical utility of NGS tests for myeloid malignancies. Hiroshima University aimed to establish a framework where the NGS-based testing would become a routine part of clinical diagnosis for myeloid neoplasms.

Following the adoption of the SOPHiA DDM Platform, Masatoshi Nishizawa from Hiroshima University presented a research case study at the 83^rd Annual Meeting of Japanese Society of Hematology (Sendai, September 23-25, 2021). Leveraging the SOPHiA DDM Platform’s unique algorithmic capabilities, the researchers from Hiroshima University detailed their experience with the first 24 samples of myeloid solution collected and analyzed as part of a research project to evaluate the clinical utility of NGS testing for myeloid malignancies. The evaluation showed that the SOPHiA DDM platform’s unique capabilities in support of NGS testing were both useful and feasible in identifying druggable targets and making precise diagnosis and prognosis to help benefit more patients in Japan. The work of Hiroshima University has since been shared with Japanese laboratories and clinicians, and the university aims to continue its evaluation with additional samples over the next 12 months.

“SOPHiA GENETICS is committed to improving patient outcomes through the practice of data driven medicine. We work with several oncohematology centers around the world and are now eager to start supporting the Japanese oncohematology network of hospitals. The more data we compute, the more benefit we bring to all our users to ultimately accelerate the democratization of data-driven-medicine,” said Jurgi Camblong, co-founder and CEO of SOPHiA GENETICS.

“To make a personalized treatment in the real-world practice of oncohematology prevail, the sophistication of diagnostic gene panels is strongly desired,” said Tatsuo Ichinohe, Director of the Department of Hematology and Oncology at Hiroshima University Hospital. “SOPHiA GENETICS’ Myeloid Plus Solution is one of the best examples I have ever seen in terms of its ease of use and wide coverage.”

SOPHiA GENETICS’ partnership with Hiroshima University follows the company’s March 2021 announcement of a long-term collaboration agreement with Hitachi, Ltd. To bring clinical, genomic, and real-world insights to more Japanese healthcare providers and pharmaceutical and biopharmaceutical companies. In partnership with Hitachi, discussions continue with additional Japanese institutions who may also benefit from SOPHiA GENETICS for oncohematological cancer research.

About SOPHiA GENETICS

SOPHiA GENETICS (Nasdaq: SOPH) is a healthcare technology company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-based SaaS platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by more than 780 hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn and Instagram. Where others see data, we see answers.

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures, unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.

SOPHiA GENETICS Forward-Looking Statements:

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof . We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Media Contact:
Eliza Bamonti
[email protected]