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SOPHiA GENETICS and AstraZeneca Spain expand HRD testing program to support molecular diagnosis of ovarian cancer in Spain
Boston, MA, Rolle, Switzerland and Madrid, Spain, February 7, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced it has expanded an existing program in Spain to increase access to local testing for homologous recombination deficiency (HRD) throughout the country. The expansion of the program, supported by AstraZeneca Spain and its network throughout the country, will further SOPHiA GENETICS’ commitment to global health equity by making this vital testing available to thousands more patients in the country.
The program from SOPHiA GENETICS and AstraZeneca Spain started in 2022, when AstraZeneca and SOPHiA GENETICS collaborated to deploy HRD testing to five labs throughout the country. In just six weeks on average, the labs were ready to start processing samples, allowing them to process tumor samples in an expedient manner. This collaboration allowed for over 4,000 samples to be analyzed to-date, equating to approximately 90 percent of HRD testing available for patients in Spain.
With today’s announcement, AstraZeneca Spain named SOPHiA GENETICS its preferred partner in deploying HRD testing throughout Spain. Together, SOPHiA GENETICS and AstraZeneca are offering the option for HRD testing to become available to even more laboratories throughout the country to help facilitate in-house HRD detection. The testing will not only aid in identifying HRD-positive tumors but will support faster diagnostics by increasing the volume and speed of next-generation sequencing (NGS) testing and tumor profiling available. By deploying the SOPHiA DDM™ Platform across further labs, the companies aim to increase accelerated diagnostics for patients and support clinicians in precision treatment planning.
For Marta Moreno, director of Corporate Affairs and Market Access of AstraZeneca Spain, “At AstraZeneca we are focused on putting the medicine precision available to patients collaborating with hospitals and reference centers throughout Spain. Thanks to the study of biomarkers we can improve the approach to cancer patients, giving them treatment with greater guarantee of effectiveness and as personalized as possible, complying with our goal of chronicling cancer and getting rid of it someday as a cause of death. Hence our agreement with SOPHiA GENETICS, to offer hospital centers throughout Spain the possibility of making an accurate diagnosis for patients with ovarian cancer.”
“The ability for local facilities in Spain to test for HRD status is paramount to providers in the region developing data-driven treatment plans to help increase positive health outcomes,” said Kevin Puylaert, Managing Director, EMEA, SOPHiA GENETICS. “We are excited to expand our testing program across several local diagnostic facilities. This program will not only make a difference to those who receive testing but will increase the volume of global data on HRD to help further progress on treatment options for those facing ovarian cancer.”
HRD is caused by a cell’s impaired ability to repair DNA double-stranded breaks through the homologous recombination repair (HRR) pathway; it is an important predictor of tumor response to certain treatment options. HRD is linked with the development of several cancers, including advanced ovarian cancer, and is the most prevalent alteration in ovarian cancer1, with approximately half of all newly diagnosed patients having HRD-positive tumors2.
About AstraZeneca Spain
AstraZeneca (LSE/STO/Nasdaq: AZN) is a global, science-led biopharmaceutical company focused on the discovery, development and commercialization of prescription medicines in Oncology, Rare Diseases and Biopharma, including Cardiovascular, Renal and Metabolism, and Respiratory and Immunology. Headquartered in Cambridge, United Kingdom, AstraZeneca operates in more than 100 countries and its innovative medicines are used by millions of patients around the world.
AstraZeneca is a Top Employers in Spain and Europe and has been awarded the EFR certificate for a Family Responsible Company.
Visit astrazeneca.es and follow the company on Twitter @AstraZenecaES and Instagram @AstraZenecaES
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products, and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
SOPHiA DDM™ Dx HRD Solution is available as a CE-IVD product for In Vitro Diagnostic Use in Europe and Turkey. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Media Contact:
Kelly Katapodis
[email protected]
Ana Navarro
[email protected]
References:
2https://www.sciencedirect.com/science/article/pii/S0923753421048286
The Hospital will use SOPHiA GENETICS technology to streamline workflows and expedite research
BOSTON and Rolle, Switzerland, December 21, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that Hôpital Saint-Louis, located in Paris, has implemented the SOPHiA DDM™ Platform to help advance its research of Myeloid Disorders and continue expanding the use of precision medicine for those in the area. This latest implementation is an expansion of its existing work with SOPHiA GENETICS.
For more than 50 years, patients suffering from Myeloproliferative neoplasms (MPNs), a subset of myeloid malignancies in which too many blood stem cells mature into red blood cells, white blood cells, or platelets, have been referred to the team at Hôpital Saint-Louis, where the Cellular Biology Department is focused on in-depth clinical research to help provide comprehensive care for MPN patients. The implementation of the SOPHiA DDM™ Platform will help the Cellular Biology Department expedite its research and increase its ability to provide data-driven care to patients with MPN.
“While the providers and researchers in my department have decades of experience with MPNs and are well-versed in providing the highest quality care to our patients, we have been pleased with the support of the innovative technology that SOPHiA GENETICS offers,” said Bruno Cassinat, PharmD, Ph.D., Molecular Diagnostics, Hôpital Saint-Louis. “The SOPHiA DDM™ Platform has been an essential tool to support us in streamlining our bioinformatics workflows, expediting our research, and making data-driven decisions for our patient population.”
MPNs originate from hematopoietic disruptions in the myeloid lineage. Advances in the study of MPNs depend on timely, cost-effective, and reliable sequencing strategies. With the SOPHiA DDM™ Platform, the Cellular Biology Department will provide its patients with access to tailored next-generation sequencing (NGS)-based workflows that enable accurate and sensitive characterization of the complex mutational landscape associated with myeloid neoplasms. These workflows will provide researchers with high-quality, reproducible data on up-to-date gene panels to expedite and advance research.
“As we continue expanding the use of data-driven medicine around the world, we are keenly focused on aiding hospitals and labs with their efforts to keep up with expanding international recommendations and the near-constant progress being made in targeted therapies for myeloid disorders,” said Kevin Puylaert, Managing Director, EMEA, SOPHiA GENETICS. “The SOPHiA DDM™ Platform is designed to ensure our customers not only have access to NGS workflows, but have the tools they need to identify insights that will help guide research, accelerate studies, and inform decision-making.”
Molecular profiling via next-generation sequencing (NGS) is used to best investigate the pathogenic variants causing different myeloid malignancies, however, NGS produces a vast amount of complex data. The SOPHiA DDM™ Platform is a NGS-based application that uses artificial intelligence (AI) to efficiently analyze and interpret raw NGS data for researchers. The Platform provides streamlined insights in a matter of days, enabling clinicians to more quickly make data-driven recommendations to their patients.
For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
SOPHiA DDM™ Dx Myeloid Solution is available as a CE-IVD product for In Vitro Diagnostic Use in Europe and Turkey. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Media Contact:
Kelly Katapodis
[email protected]
OmiCure uses the SOPHiA DDM™ Platform to advance its testing technology
BOSTON, United States and Rolle, Switzerland, December 21, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that OmiCure®, a leading European digital health company, is live on the SOPHiA DDM™ Platform. OmiCure, which works to expand the use of data-driven medicine via its tumor profiling tests, will use SOPHiA GENETICS’ technology to enhance its offerings in support of physicians and patients.
OmiCure, which was launched in November 2019 as a spin-off of Ariana Pharma, provides state-of the-art interpretation tools to oncologists to aid them in the use of precision medicine, specifically for complex, rare or treatment-resistant cancers. The company offers a range of molecular assays using both genomics and transcriptomics data, and proprietary comprehensive AI therapeutic decision support algorithms. The OmiCure platform provides a deep level of understanding to clinicians, helping them in their informed treatment decision. The SOPHiA DDM™ Platform, which is a cloud-based platform that uses artificial intelligence (AI), will help streamline OmiCure’s tests and algorithms.
“The work we do at OmiCure is personalized and time sensitive, and the ability to use the best towards getting fastest and most accurate results is paramount to the success of our company,” said Thomas Turcat, Founder and COO of OmiCure. “By using the SOPHiA DDM™ Platform we are enhancing our testing and helping to advance the industry’s use of data-driven medicine to create the most personalized treatment plans.”
Since it launched in 2019, OmiCure has been investing in the development of tumor profiling testing tools based on the sequencing and analysis of DNA and RNA. This testing relies on next-generation sequencing (NGS) to help identify key biomarkers. However, NGS can produce a vast dataset. The SOPHiA DDM™ Platform gives access to a fully integrated bioinformatic workflow that helps quickly synthesize the large volume of data that comes with NGS tests. The Platform combines analytical performance with streamlined interpretation of complex genomic variants from comprehensive genomic profiling.
“We work daily at SOPHiA GENETICS to provide technology and solutions that may have the ability to improve care and outcomes,” said Kevin Puylaert, Managing Director, EMEA, SOPHiA GENETICS. “The SOPHiA DDM™ Platform provides highly accurate insights from multiple genomic alterations across a broad panel of genes and provides organizations like OmiCure valuable insights to inform oncologists on treatment options for patients with challenging cancers. We are excited to support OmiCure in advancing its products and expanding the use of data-driven medicine.”
With SOPHiA GENETICS' global data-sharing network, OmiCure will be able to offer physicians clinically actionable insights from data to help improve patient outcomes worldwide. In addition, the technology will aid OmiCure in creating a more robust in-house database that can be used to help increase its team’s expertise with each test.
For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
About OMICURE
OMICURE® SAS is a leading European digital health precision medicine company, that developpes and markets genomic diagnostic oncology products which support physicians with their complex treatment decisions in cancer care. OMICURE®’s technology combines a proprietary advanced, comprehensive analytical xAI platform (explainable Artificial Intelligence platform) that analyzes all clinically relevant cancer biomarkers (DNA, RNA and protein profiles) from both solid and liquid biopsies with its curated cancer treatments knowledge database which continuously learns from cutting-edge, validated, scientific and medical advances. This one-stop-shop analysis and interpretation service gives oncologists actionable results to enable the selection of treatments tailored to the individual patient’s cancer profile.
OMICURE® provides to Anti-Cancer centers, oncologists, and physicians in the world an access to a state-of the-art interpretation to improve their routine oncology-oriented analyses. The xAI platform processes oncology raw NGS and molecular biology data to turn them into clinical insights such as treatment options or clinical trials.
For more information, visit: https://www.omicure.com/
Media Contact:
Kelly Katapodis
[email protected]
BOSTON & ROLLE, Switzerland (December 14, 2023) --- SOPHiA GENETICS (NASDAQ: SOPH) today announced that Jurgi Camblong, PhD., Chief Executive Officer and Co-founder, is scheduled to present at the J.P. Morgan 2024 Healthcare Conference on Thursday, January 11, 2024, at 9:00 a.m. PST in San Francisco.
Live, listen-only webcasts of this presentation can be accessed by visiting the Investors section of the SOPHiA GENETICS website at ir.sophiagenetics.com. A replay of the webcast will be available shortly after the conclusion of the presentation and archived on the company's website for two weeks following the presentation.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
Investor Contact:
Kellen Sanger
[email protected]
Media Contact:
Kelly Katapodis
[email protected]
World-class liquid biopsy testing will be available to SOPHiA GENETICS customers
Boston, MA and Rolle, Switzerland, December 7, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced an expanded suite of solutions under SOPHiA DDM™ for Liquid Biopsy. The range of solutions, including MSK-ACCESS® powered with SOPHiA DDM™ and custom solutions, will help progress oncology research and tumor mutation profiling. The rollout of SOPHiA GENETICS’ liquid biopsy capabilities demonstrates the company’s commitment to developing advanced solutions that empower timely, critical decision-making and improve health outcomes.
For a sizeable number of cases, genomic testing of tumor tissue is not feasible due to either insufficient tissue material, low quality of the obtained tissue, or the invasiveness of the procedure. Liquid biopsy testing offers an alternative to solid tumor testing by isolating cell-free DNA (cfDNA) from blood plasma, which may uncover circulating tumor DNA (ctDNA). Isolating these DNA samples from a simple blood draw can help guide clinical decisions in a manner that is faster and less invasive, expedite results for researchers and clinicians, and simplify monitoring. SOPHiA GENETICS’ liquid biopsy offering will help users enhance tumor profiling with advanced cfDNA analysis and a streamlined DNA-only NGS workflow, allowing users to go from extracted cfDNA to comprehensive report in an efficient timeframe. SOPHiA DDM™ for Liquid Biopsy features SOPHiA GENETICS’ proprietary unique molecular identifier technology (CUMIN™) that is designed to transform the way labs analyze cell-free DNA samples with exceptional performance and reliable results.
“Our goal at SOPHiA GENETICS is to increase the use of data-driven medicine around the world and decrease health inequities by making resources more accessible to all,” said Philippe Menu, MD, PhD., Chief Medical Officer and Chief Product Officer, SOPHiA GENETICS. “Liquid biopsy is a sophisticated testing capability that can help expedite clinical decisions and planning. It is inherently cheaper and faster than traditional biopsy methods and is an excellent tool for labs and health systems to have at their disposal. We feel strongly that increased use of liquid biopsy will help advance oncology care and we are excited to help our customers implement this offering.”
Customers interested in implementing a liquid biopsy offering via SOPHiA DDM™ have different options based on their individual needs. MSK-ACCESS® powered with SOPHiA DDM™ is a decentralized version of a highly validated ctDNA assay developed by Memorial Sloan Kettering (MSK) that involves the deep sequencing of 146 key cancer-associated genes. Customers utilizing the SOPHiA DDM™ Platform for solid tumor applications can adapt their panels to include liquid biopsy samples; and for customers who have unique challenges or who focus on specific biomarkers, SOPHiA GENETICS offers custom liquid biopsy applications built in partnership with the SOPHiA GENETICS team.
The SOPHiA GENETICS liquid biopsy solutions incorporate the company’s state-of-the-art proprietary algorithms and advanced genomic analysis, made possible with artificial intelligence (AI), to provide customers with expedited and streamlined insights that increase the ability of clinician researchers to practice precision medicine. Additionally, the SOPHiA GENETICS solutions allow customers to retain full ownership of their databases and obtain reproducible data that can help accelerate future work.
The SOPHiA GENETICS liquid biopsy solutions are now available for customers worldwide. Learn more about clinical applications for liquid biopsy testing here, and for more information on SOPHiA DDM™ for Liquid Biopsy, visit SOPHiAGENETICS.com or connect on X, LinkedIn, Facebook, and Instagram.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures, unless specified otherwise. MSK-ACCESS® powered with SOPHiA DDM™ is a product in development and may not be available for sale. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Media Contact:
Kelly Katapodis
[email protected]
Through the expanded relationship CHU de Nîmes will advance its research of rare and inherited diseases through pharmacogenomics
BOSTON and Rolle, Switzerland, November 30, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that it has expanded its work with CHU de Nîmes, a regional and university hospital located in the South of France. The hospital system will use the SOPHiA DDM™ Platform to progress its pharmacogenomics research.
Pharmacogenomics research is a field of research that looks at how an individual’s unique genetic profile can affect response to medications, with the long-term goal to support clinicians in their choice of drugs and doses to best treat their patients.
“As precision medicine continues to become the gold standard of care, it’s essential that hospitals and organizations like CHU de Nîmes have access to technologies to help streamline research and treatment planning, starting with identifying how an individual’s genetic profile influences response to a certain medication” said Kevin Puylaert, Managing Director, EMEA, SOPHiA GENETICS. “With the SOPHiA DDM™ Platform, CHU de Nîmes will be able to advance its pharmacogenomics work, with the aim to bring about a broader use of personalized treatment plans for the French patient population.”
CHU de Nîmes is a member of the French-speaking group RNPGx, an international organization of some of the top researchers in the field of pharmacogenomics. RNPGx aims to further the adoption and implementation of pharmacogenetics testing.
Top researchers from RNPGx member institutions collaborated with SOPHiA GENETICS to develop a pharmacogenomics panel. The panel is a targeted, capture-based NGS panel that will expedite the process of testing and accelerate pharmacogenomics research. Additionally, the analytical capabilities of the SOPHiA DDM ™ Platform provide CHU de Nîmes with streamlined insights to facilitate fast and accurate variant discovery and reporting.
CHU de Nîmes also uses SOPHiA GENETICS’ technology for its research and treatment planning for autism and research of blood cancers. With the expanded relationship, CHU de Nîmes will continue to retain ownership of its research database, building upon the work already done through its use of SOPHiA GENETICS and helping increase the team’s expertise in a variety of research areas.
For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Media Contact:
Kelly Katapodis
[email protected]
Largest health center in Italy uses SOPHiA DDM™ Platform on Microsoft Azure to expand data-driven medicine capabilities while ensuring accuracy and security
BOSTON and ROLLE, Switzerland, November 28, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company in the healthcare space and a leader in data-driven medicine, today announced the expansion of its relationship with the Città della Salute e della Scienza di Torino located in Turin, Italy. The hospital, which used SOPHiA GENETICS after a public tender in 2021 to optimize workflows and support research in the areas of hereditary cancer, neurological disorders, solid tumors, hematology and rare disease, will further expand its usage of the SOPHiA DDM™ Platform to support research on homologous recombination repair (HRR) biomarkers that indicate treatment options for ovarian, prostate, breast and pancreatic cancers.
Città della Salute e della Scienza di Torino is part of one of the largest university hospitals and health systems in Europe. As such, the institution cares for thousands of people each year and is responsible for the efficient, accurate and secure analysis of a vast amount of genomic data.
“The ability to partner with a technology provider that can help efficiently decipher the expansive amount of data from raw next generation sequencing (NGS) data – and guarantee security of such data – is of paramount importance to our institution,” said Dr. Barbara Pasini, Head of the Medical Genetics Unit, Città della Salute e della Scienza di Torino. “The SOPHiA DDM™ Platform, which leverages the cloud infrastructure of Microsoft Azure, answers our needs by providing the secure analysis of all data coupled with simplified insights.”
NGS is helping to revolutionize the research of several cancers and rare diseases, yet it yields extremely large and complex datasets for analysis. The Microsoft Azure-powered SOPHiA DDM™Platform uses artificial intelligence and machine learning with patented technologies to streamline the analysis of raw NGS data and generate biologically actionable insights, which can speed the research process and ultimately lead to better health outcomes.
SOPHiA GENETICS has worked with Microsoft to further the democratization of data-driven medicine. Using the secure, cloud-based infrastructure of Microsoft Azure, SOPHiA GENETICS offers a solution via the SOPHiA DDM™ Platform that helps break the data silos and facilitate data-sharing and research advancements.
“The SOPHiA DDM™ Platform has helped us to optimize our research in specific cancer types, such as the recently added analysis on ovarian and prostate tumors, that may contain somatic BRCA1 and BRCA2 gene variants. The platform has enabled our researchers analyzing tumor samples to more quickly come to data-driven conclusions and move towards the practice of precision medicine,” said Dr. Francia di Celle and Dr. Bonello, of the Molecular Pathology Laboratory, Città della Salute e della Scienza di Torino.
“The partnership between SOPHiA GENETICS and Microsoft provides clients such as Città della Salute e della Scienza di Torino with convenience and flexibility to implement the technology solutions necessary to suit their needs, while ensuring peace of mind that their data is secure,” said Kevin Puylaert, Managing Director, EMEA, SOPHiA GENETICS. “We are excited to be expanding our work with organizations that recognize the innovative power of precision medicine and the elevated standard of care it can provide to patients.”
“Together we're not only enhancing operational efficiency but also unveiling unprecedented potential within medical and genomic data landscapes by leveraging Azure for data ingestion and data management in the SOPHiA DDM™ Platform. This new era of cooperation allows healthcare providers to bolster their capabilities in managing multimodal data, which paves the way for deriving profound insights conducive to enhanced patient care," said Elena Bonfiglioli, General Manager, WW Healthcare, Global Pharma and Life Sciences, Microsoft. “Microsoft is pleased to continue supporting SOPHiA GENETICS’ mission to democratize data-driven medicine by providing secure and scalable cloud infrastructure.”
For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn,Facebook, and Instagram.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native software company in the healthcare space dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures, unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA DDM™ miniHRS Solution is available as a CE-IVD product for In Vitro Diagnostic Use in Europe and Turkey. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Media Contact:
Kelly Katapodis
[email protected]
The SOPHiA DDM™ Platform used by IHG PAS to advance its research of male infertility
BOSTON and Rolle, Switzerland, November 17, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that the Institute of Human Genetics, Polish Academy of Sciences (IHG PAS), the leading center for genetics research in Poland, is now live on the SOPHiA DDM™ Platform. IHG PAS will use SOPHiA GENETICS to advance its research into rare disorders, in particular male fertility.
It is estimated that roughly one in six people worldwide will be affected by infertility in their lifetime. As a staple in the medical research community of Poland, IHG PAS specializes in a variety of research areas, including reproductive biology. By using the SOPHiA DDM™ Platform, the Department of Reproductive Biology and Stem Cells at IHG PAS intends to further their research in the area of male infertility, via next-generation sequencing (NGS) for genetic assessment of infertility.
“The research we do at IHG PAS is used broadly throughout Poland due to our deep-rooted relationships with the surrounding medical community and our nearly 50-year history,” said Marta Olszewska, Assistant Professor, Head of the Research Team of Sperm Genetics, IHG PAS. “With the implementation of the SOPHiA DDM™ Platform, our team is now able to expedite their research and provide our partners with accelerated findings that can positively impact the comprehension of infertility.”
IHG PAS will be using the SOPHiA DDM™ Whole Exome Solution (WES), which is a next-generation sequencing (NGS)-based application that provides a streamlined end-to-end workflow, from sample to variant report, to accelerate research of inherited diseases, including infertility. Using the SOPHiA DDM™ Platform, IHG PAS will have analyzed results and streamlined insights in an efficient timeframe.
“The advanced analytical analysis provided by the SOPHiA DDM™ Platform provides overnight analysis of WES and has the rich knowledge base to help identify variants of interest associated with rare diseases.” said Kevin Puylaert, Managing Director, EMEA, SOPHiA GENETICS. “In addition, the decentralized nature of the SOPHiA DDM™ Platform creates a collective intelligence from all of the platform’s users around the world can help better inform researchers studying rare disorders, including the researchers at IHG PAS."
With the SOPHiA DDM™ Platform, IHG PAS will retain complete ownership of its database, supporting its research team as it continues to increase its expertise and build upon its learnings.
For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on Twitter, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Media Contact:
Kelly Katapodis
[email protected]
References: 1 https://www.who.int/news/item/04-04-2023-1-in-6-people-globally-affected-by-infertility
Record results on growth acceleration, significant improvement in operating loss and cash burn
BOSTON, United States and ROLLE, Switzerland, November 7, 2023 — SOPHiA GENETICS SA (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today reported financial results for the third quarter ended September 30, 2023.
Recent Highlights
CEO Commentary
“We delivered an outstanding third quarter, highlighted by 37% year-over-year constant currency ex. COVID-19 revenue growth. Our growth came across the breadth of our portfolio areas and geographies, despite the currently challenging macro environment. Our strong performance was complemented by continued improvements to gross margins and operating expenses, including a marked 39% improvement in year-over-year adjusted operating loss and a significant reduction in our cash burn.” said Jurgi Camblong, PhD., Chief Executive Officer and Co-founder of SOPHiA GENETICS. “The team at SOPHiA GENETICS continues to drive innovation and growth in the area of technology-agnostic artificial intelligence (AI) software for genomic and multimodal analysis, and the recurring nature of our revenues positions us well to weather economic uncertainty, as we finish this year and look ahead to 2024.”
Ecosystem Update
In October, SOPHiA GENETICS announced that Memorial Sloan Kettering (MSK) and AstraZeneca would be collaborating jointly with SOPHiA GENETICS to bring high quality, comprehensive cancer testing to a global scale. With this collaboration, the three leading organizations will further their shared goal to advance health equity on a global scale by providing inclusive access to comprehensive cancer testing worldwide.
The partnership will provide MSK’s proprietary liquid biopsy and solid tumor cancer tests – MSK-ACCESS® and MSK-IMPACT® – to organizations worldwide via our decentralized, technology agnostic SOPHiA DDM™ Platform. This offering will be rapidly deployed by SOPHiA GENETICS with support from AstraZeneca’s global footprint. Through SOPHiA GENETICS’ cloud-based platform, which provides highly accurate and reliable data and insights, institutions around the world – and in traditionally under-resourced and under-served areas – will have the power to make data-driven decisions.
We are also pleased to announce that BioReference®, a reference laboratory based outside of New York City which processes over 12 million tests annually, primarily through community oncologists, will be among the first to add circulating tumor (ct)DNA testing via liquid biopsy to its offerings with MSK-ACCESS® powered with SOPHiA DDM™.
Beyond MSK-ACCESS®, SOPHiA GENETICS has also seen increased demand for decentralized liquid biopsy testing and is pleased to announce today that Centre Léon-Bérard (CLB), part of the CLCC network, consisting of 19 regional-cancer centers in France, will use a liquid biopsy application on SOPHiA DDM™ by leveraging SOPHiA GENETICS’ proprietary CUMIN technology.
Third Quarter Financial Results
Total revenue for the third quarter of 2023 was $16.3 million compared to $11.6 million for the third quarter of 2022, representing year-over-year growth of 40%. Constant currency revenue growth was 33%, and constant currency revenue growth excluding COVID-19-related revenue was 37%.
Platform analysis volume, including volume from Integrated access, increased to 79,784 analyses for the third quarter of 2023 compared to 62,276 analyses for the third quarter of 2022. The year-over-year growth of 28% was attributable to growth in Core Platform analysis volume, partially offset by the continued decline of COVID-19-related analysis volume. Excluding COVID-related volume, Platform analysis volume was 78,709 for the third quarter of 2023 compared to 57,707 in the third quarter of 2022, representing 36% year-over-year growth.
Gross profit for the third quarter of 2023 was $11.3 million compared to gross profit of $7.3 million in the third quarter of 2022, representing year-over-year growth of 55%. Gross margin was 69% for the third quarter of 2023 compared with 63% for the third quarter of 2022. Adjusted gross profit was $11.8 million, an increase of 56% compared to adjusted gross profit of $7.6 million in the third quarter of 2022. Adjusted gross margin was 73% for the third quarter of 2023 compared to 67% for the third quarter of 2022.
Total operating expenses for the third quarter of 2023 were $27.8 million compared to $30.9 million for the third quarter of 2022.
R&D expenses for the third quarter of 2023 were $9.0 million compared to $10.1 million for the third quarter of 2022.
Sales and marketing expenses for the third quarter of 2023 were $6.8 million compared to $7.9 million for the third quarter of 2022.
General and administrative expenses for the third quarter of 2023 were $12.7 million compared to $12.8 million for the third quarter of 2022.
Operating loss for the third quarter of 2023 was $16.5 million compared to $23.6 million in the third quarter of 2022. Adjusted operating loss for the third quarter of 2023 was $11.8 million compared to $19.3 million for the third quarter of 2022. Cash burn for the third quarter of 2023 was $15.8 million, compared to $27.4 million in the third quarter of 2022.
Net loss for the third quarter of 2023 was $13.8 million or $0.21 per share compared to $23.3 million or $0.36 per share in the third quarter of 2022.
Cash and cash equivalents were $132.8 million as of September 30, 2023.
2023 Outlook
The company is reaffirming its previously provided guidance of:
Constant currency revenue growth excluding COVID-19-related revenue is a non-IFRS measure. See “Presentation of Constant Currency Revenue and Excluding COVID-19-Related Revenue” below for a description of its calculation. The company is unable to provide a reconciliation of forward-looking constant currency revenue growth excluding COVID-19-related revenue to revenue, the most comparable IFRS financial measure, due to the inherent difficulty in forecasting and quantifying the impact of foreign currency translation.
Webcast and Conference Call Information
SOPHiA GENETICS will host a conference call and live webcast to discuss the third quarter of 2023 financial results as well as business outlook on Tuesday, November 7, 2023, at 8:00 a.m. (08:00) Eastern Time / 2:00 p.m. (14:00) Central European Time. The call will be webcast live on the SOPHiA GENETICS Investor Relations website. The conference call can also be accessed live over the phone by dialing 1-800-715-9871 (United States) or 1-646-307-1963 (outside of the United States). Additionally, an audio replay of the conference call will be available on the SOPHiA GENETICS website after its completion.
About SOPHiA GENETICS
SOPHiA GENETICS SA (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM or connect on Twitter, Facebook, LinkedIn, and Instagram. Where others see data, we see answers.
Non-IFRS Financial Measures
To provide investors with additional information regarding the company’s financial results, SOPHiA GENETICS has disclosed here and elsewhere in this earnings release the following non-IFRS measures:
These non-IFRS measures are key measures used by SOPHiA GENETICS management and board of directors to evaluate its operating performance and generate future operating plans. The exclusion of certain expenses facilitates operating performance comparability across reporting periods by removing the effect of non-cash expenses and certain variable charges. Accordingly, the company believes that these non-IFRS measures provide useful information to investors and others in understanding and evaluating its operating results in the same manner as its management and board of directors.
These non-IFRS measures have limitations as financial measures, and you should not consider them in isolation or as a substitute for analysis of SOPHiA GENETICS’ results as reported under IFRS. Some of these limitations are:
Because of these limitations, you should consider these non-IFRS measures alongside other financial performance measures, including various cash flow metrics, net income and other IFRS results.
The tables below provide the reconciliation of the most comparable IFRS measures to the non-IFRS measures for the periods presented.
Presentation of Constant Currency Revenue and Excluding COVID-19-Related Revenue
SOPHiA GENETICS operates internationally, and its revenues are generated primarily in the U.S. dollar, the euro and Swiss franc and, to a lesser extent, British pound, Australian dollar, Brazilian real, Turkish lira and Canadian dollar depending on the company’s customers’ geographic locations. Changes in revenue include the impact of changes in foreign currency exchange rates. We present the non-IFRS financial measure “constant currency revenue” (or similar terms such as constant currency revenue growth) to show changes in revenue without giving effect to period-to-period currency fluctuations. Under IFRS, revenues received in local (non-U.S. dollar) currencies are translated into U.S. dollars at the average monthly exchange rate for the month in which the transaction occurred. When the company uses the term “constant currency”, it means that it has translated local currency revenues for the current reporting period into U.S. dollars using the same average foreign currency exchange rates for the conversion of revenues into U.S. dollars that we used to translate local currency revenues for the comparable reporting period of the prior year. The company then calculates the difference between the IFRS revenue and the constant currency revenue to yield the “constant currency impact” for the current period.
The company’s management and board of directors use constant currency revenue growth to evaluate growth and generate future operating plans. The exclusion of the impact of exchange rate fluctuations provides comparability across reporting periods and reflects the effects of customer acquisition efforts and land-and-expand strategy. Accordingly, it believes that this non-IFRS measure provides useful information to investors and others in understanding and evaluating revenue growth in the same manner as the management and board of directors. However, this non-IFRS measure has limitations, particularly as the exchange rate effects that are eliminated could constitute a significant element of its revenue and could significantly impact performance and prospects. Because of these limitations, you should consider this non-IFRS measure alongside other financial performance measures, including revenue and revenue growth presented in accordance with IFRS and other IFRS results.
In addition to constant currency revenue, the company presents constant currency revenue excluding COVID-19-related revenue to further remove the effects of revenues that are derived from sales of COVID-19-related offerings, including a NGS assay for COVID-19 that leverages the SOPHiA DDMTM Platform and related products and solutions analytical capabilities and COVID-19 bundled access products. SOPHiA GENETICS do not believe that these revenues reflect its core business of commercializing its platform because the company’s COVID-19 solution was offered to address specific market demand by its customers for analytical capabilities to assist with their testing operations. The company does not anticipate additional development of its COVID-19-related solution as the pandemic transitions into a more endemic phase and as customer demand continues to decline. Further, COVID-19-related revenues did not constitute, and the company does not expect COVID-19-related revenues to constitute in the future, a significant part of its revenue. Accordingly, the company believes that this non-IFRS measure provides useful information to investors and others in understanding and evaluating its revenue growth. However, this non-IFRS measure has limitations, including that COVID-19-related revenues contributed to the company’s cash position, and other companies may define COVID-19-related revenues differently. Because of these limitations, you should consider this non-IFRS measure alongside other financial performance measures, including revenue and revenue growth presented in accordance with IFRS and other IFRS results.
The table below provides the reconciliation of the most comparable IFRS growth measures to the non-IFRS growth measures for the current period.
Forward-Looking Statements
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding SOPHiA GENETICS future results of operations and financial position, business strategy, products and technology, partnerships and collaborations, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on SOPHiA GENETICS’ management’s beliefs and assumptions and on information currently available to the company’s management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in the company’s filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of its date. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in the company’s expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Investor Contact
Investor Relations
[email protected]
Media Contact
Kelly Katapodis
Senior Manager, Media & Communications
[email protected]
Notes to the Reconciliation of IFRS to Adjusted Financial Measures Tables
World-class liquid biopsy testing will be made commercially available to BioReference® customers across the country
BOSTON MA, ELMWOOD PARK, NJ, and Rolle, Switzerland, November 7, 2023 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that BioReference® Health, LLC, an OPKO Health, Inc. company and full-service laboratory that processes more than 12 million tests annually, will implement SOPHiA GENETICS’ technology and add MSK-ACCESS® liquid biopsy to its test suite. With the implementation of SOPHiA GENETICS, BioReference will be the first laboratory globally to adopt MSK-ACCESS® powered with SOPHiA DDM™. The offering will be commercially available for ordering by healthcare providers through BioReference, and its specialty division, GenPath® Oncology in 2024.
Since January 2023, Memorial Sloan Kettering Cancer Center (MSK) and SOPHiA GENETICS have been working on merging MSK-ACCESS® technology with the SOPHiA DDM™ Platform algorithms to provide a comprehensive liquid biopsy assay available on the decentralized platform. The new offering takes advantage of the sophisticated analytics of the SOPHiA DDM™ Platform, combining its state-of-the-art algorithms and global network with the scientific and clinical expertise of MSK in cancer genomics. The onboarding of BioReference aims to bring access to world-class liquid biopsy testing to the laboratory’s customers across the country.
“The availability of MSK-ACCESS® powered with SOPHiA DDMTM will support pioneer laboratories like BioReference taking their genomic analysis capabilities to the next level, by enhancing their ability to serve their customers with a cutting-edge liquid biopsy assay,” said Philippe Menu, M.D., PhD., Chief Medical Officer and Chief Product Officer, SOPHiA GENETICS. “We are eager to begin implementation with BioReference and help bring this critical cancer testing technology to more areas throughout the U.S., including rural and underserved populations.”
BioReference currently operates 10 laboratory facilities across the U.S. and provides scientific expertise in oncology, urology, and women’s health. The laboratory’s oncology division, GenPath Oncology, offers a comprehensive portfolio to support the continuum of care of cancer patients – from risk assessment to treatment planning. Deploying in-house liquid biopsy testing will enable the laboratory to analyze samples from a simple, non-invasive blood draw, allowing for less invasive monitoring of cancers. The offering will incorporate SOPHiA GENETICS’ advanced genomic analysis, made possible with artificial intelligence (AI), and expedited streamlined insights to increase the ability of clinician researchers to practice precision medicine.
“We’re proud to be the first commercial laboratory to be able to offer this liquid-based technology,” said Ellen Beausang, Chief Commercial Officer, BioReference. “The adoption of the SOPHiA GENETICS platform along with MSK’s oncology genomics technology signals our ongoing and unwavering commitment to improving cancer care for patients, and offering advanced tools and solutions that empower timely and critical decision-making for healthcare providers and patient outcomes.”
MSK-ACCESS® powered with SOPHiA DDM™ is being designed to align with the most up-to-date guidelines and clinical trial data, reflecting major biologically actionable biomarkers. In addition to quickly providing analysis and insights, the SOPHiA DDM™ Platform will allow BioReference to retain ownership of its database and obtain reproducible data that can help accelerate future work.
For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram.
For more information on BioReference, visit https://www.bioreference.com/, or connect on LinkedIn, Instagram, Facebook and X.
About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a software company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-native platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by a broad network of hospital, laboratory, and biopharma institutions globally. For more information, visit SOPHiAGENETICS.COM, or connect on X, LinkedIn, Facebook, and Instagram. Where others see data, we see answers.
About BioReference Health, LLC
BioReference® Health LLC, an OPKO Health, Inc. Company (NASDAQ: OPK), empowers confident healthcare decisions by prioritizing service, creating innovative solutions, and offering scientific expertise in oncology, urology, and women’s health. Headquartered in Elmwood Park, New Jersey, BioReference operates 10 laboratory facilities around the country, is in-network with the largest health plans in the United States and processes more than 12 million tests annually. BioReference provides credible and tailored solutions for a variety of customers and patients, including medical practices small and large, hospitals and health systems, correctional institutions, government agencies, educational systems, and sport leagues. In addition to an extensive test menu with 99 percent of tests performed in-house, BioReference’s differentiated offerings include large-scale health screening programs, on-demand mobile phlebotomy, and transformative business solutions that optimize laboratory management. For more information visit https://www.bioreference.com/.
MSK-ACCESS® powered with SOPHiA DDM™ is a product in development and may not be available for sale. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence.
SOPHiA GENETICS Forward-Looking Statements:
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.
Media Contact:
Kelly Katapodis
[email protected]
Emily Smith
[email protected]
SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise.
SOPHiA DDM™ Dx Hereditary Cancer Solution, SOPHiA DDM™ Dx RNAtarget Oncology Solution and SOPHiA DDM™ Dx Homologous Recombination Deficiency Solution are available as CE-IVD products for In Vitro Diagnostic Use in the European Economic Area (EEA), the United Kingdom and Switzerland. SOPHiA DDM™ Dx Myeloid Solution and SOPHiA DDM™ Dx Solid Tumor Solution are available as CE-IVD products for In Vitro Diagnostic Use in the EEA, the United Kingdom, Switzerland, and Israel. Information about products that may or may not be available in different countries and if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact us at [email protected] to obtain the appropriate product information for your country of residence.
All third-party trademarks listed by SOPHiA GENETICS remain the property of their respective owners. Unless specifically identified as such, SOPHiA GENETICS’ use of third-party trademarks does not indicate any relationship, sponsorship, or endorsement between SOPHiA GENETICS and the owners of these trademarks. Any references by SOPHiA GENETICS to third-party trademarks is to identify the corresponding third-party goods and/or services and shall be considered nominative fair use under the trademark law.