Boston, MA and Lausanne, Switzerland, November 17th, 2020: SOPHiA GENETICS, leader in Data-Driven Medicine, announced today that Bram Goorden joined its Executive team, holding the dual role of Chief Commercial Officer and Head of North America. Goorden comes to SOPHiA from Foundation Medicine Inc. (Cambridge, MA) where he held the role of VP of International Business and Partnering, in charge of expanding the company’s global footprint.

“Bram is an amazing addition to our leadership team as he is well-versed in building top performing teams and developing lasting commercial relationships with healthcare stakeholders that are of immense benefit to all involved. He will be a great driver of our US and Global expansion plans moving forward as he champions the future of Data-Driven Medicine in both the Clinical and BioPharma Business Units,” affirmed founder and CEO Jurgi Camblong. 

Bram Goorden, a Belgian national, is an accomplished commercial executive with 20 years of experience in life sciences. Before FMI, he was General Manager, Head of Therapeutics with Prometheus Labs (San Diego, CA), a Nestle Health Science company. Earlier in his career, Goorden held global revenue driving roles of increasing responsibility with Eli Lilly and UCB Pharma. He originally began his career as a management consultant at Accenture where he worked with clients in biotech, utilities and petrochemicals.

“I am thrilled to join the SOPHiA team. Our universal Platform is democratizing Data-Driven Medicine in an unparalleled fashion. Together, we enable healthcare providers to fully utilize the power of decentralized genomic and multimodal data in their efforts to improve patient outcomes. It’s a privilege to help grow access to our solution for both clinicians and biopharma partners in my role as Chief Commercial Officer,” said Bram Goorden.

Goorden is now based from the company’s US headquarters in Boston. As part of the closing of a recent successful $110 Million oversubscribed funding round, SOPHiA GENETICS has plans to nearly triple their workforce in the United States.

Supporting the Company’s Global Expansion to Meet Growing Clinical and Biopharma Demand for Data-Driven Medicine

·      SOPHiA GENETICS enters next stage of its global expansion with oversubscribed Series F round exceeding $110 million, led by major health-tech fund and followed by strategic industry leader

·      Company demonstrates solidity of its business model with banks joining in the round

·      Didier Hirsch, former CFO at Agilent, joins the company’s Board of Directors and will chair its Audit Committee

Lausanne, SWITZERLAND, and Boston, US – October 1, 2020: SOPHiA GENETICS, global leader in Data-Driven Medicine, announced today the closing of a $110 million financing round to enter into the next stage of its expansion, with a focus on supporting the growing clinical and biopharma demand for Data-Driven Medicine worldwide.

This Series F round was led by aMoon, a leading health-tech & life sciences venture fund based in Israel, and Hitachi Ventures, a venture arm of Japanese Hitachi Group. The company also received the trust of prime financial institutions Credit Suisse and the Pictet group. Existing investors Swisscom Ventures, Endeavour Vision, Generation Investment Management, Alychlo, and Eurazeo Growth participated in the round, as well as newcomers ACE & Company and Famille C Invest.

Having established the world’s largest Data-Driven Medicine community network through its universal and collaborative AI platform, SOPHiA GENETICS supports healthcare professionals by translating multiple sources of complex medical data into valuable clinical insights. The SOPHiA Platform is used by over 1’000 healthcare institutions and has analyzed 600’000 genomic profiles; up to 17’000 new profiles a month. Through continual learning and network effects, experts worldwide are empowered to act with confidence for better patient management.

The new funding round will boost the company’s penetration in both the US and Asian markets. Proceeds will also be dedicated to increasing the platform multimodal capabilities and its adoption by healthcare institutions worldwide. Leveraging this momentum, SOPHiA GENETICS will be best positioned to power biopharma’s effort to optimize and accelerate the development of new targeted therapies.

As SOPHiA enters this new phase of rapid expansion, Didier Hirsch, former CFO at Agilent, joins the company’s Board of Directors. He will also chair the company’s Audit Committee, ushering SOPHiA GENETICS toward its next important milestones.

“The overall demand for Data-Driven Medicine is rapidly growing, and the next step is to successfully combine multiple sources of data to better address clinicians’ needs,” said Dr. Tomer Berkovitz, Partner & CFO of aMoon. “With this shift, more complex data will be generated, and we believe that SOPHIA’s decentralized model will play a pivotal role in empowering health organizations to offer better patient care”.

Keiji Kojima, Executive Vice President and General Manager of Hitachi’s Smart Life Business Division, added: “Over the years, SOPHiA GENETICS has emerged as a leader in Data-Driven Medicine and we look forward to supporting the company expand its footprint in the Japanese market and beyond.”

“SOPHiA has established an impressive track record of disrupting healthcare and enabling a decentralized approach. This new funding round will further strengthen SOPHiA’s already unique offering, performance, and life-changing impact on patients and targeted therapies,” said Troy Cox, Chairman of the Board of Directors of SOPHiA GENETICS.

“Since inception, we knew that leveraging a wide range of data modalities powered by cutting-edge technologies was key to sustainably deliver better outcomes to the global healthcare community”, concluded Jurgi Camblong, CEO and Founder at SOPHiA GENETICS. “Now, with this new funding round, we can embark on the next stage of our development and take our collaborative approach further, delivering intelligent medicine, together.”

New solution to remove some of the current unknowns about the virus

Boston & Lausanne, Switzerland, August 6th, 2020:

SOPHiA GENETICS, leader in Data-Driven Medicine, launches a first-of-its-kind multimodal solution to predict COVID-19 disease evolution, opening new dimensions of insight into the fight against the worldwide pandemic.

This advancement goes beyond genomics, analyzing a wider spectrum of data to support researchers’ efforts to understand and fight the disease. SOPHiA’s unique multimodal approach aims to support containment efforts globally by demonstrating immediate benefits for community contact tracing and essential viral monitoring research. This important analysis can support paths to new protective measures and outbreak protocols around the world.

Detecting the disease and predicting its course and outcomes both continue to be major challenges for optimal COVID-19 management. There are a number of variables that can be linked to the likely disease evolution including viral strain, host genetic response factors, and clinical management of cases. By harnessing a combination of these data sources, SOPHiA GENETICS uncovers new actionable knowledge.

As part of the multimodal approach, SOPHiA GENETICS has built an AI-powered solution to conduct full-genome analysis of SARS-CoV-2. It can compare insights from the viral genomic data with human “host” genetic information. In addition, the new SOPHiA Radiomics for COVID-19 offers a CT-based automated workflow for whole-lung segmentation and disease quantification. With an easy to use interface, radiomic features are extracted from lung abnormalities and well-aerated areas. Our unique machine learning is applied to more easily discover abnormalities predictive of disease evolution and leverage upon multimodal research data sets.

“Controlling this virus means understanding it at new levels that go beyond simple testing. The evolution of the disease must be predicted in order to create containment measures. We can do this by building a world map of longitudinal tracking, beginning with highly accurate and reliable virus data, further powered by radiomic data,” said Jurgi Camblong, SOPHiA GENETICS’ Founder and CEO. “The global SOPHiA community of 1,000 plus hospitals builds upon these efforts in real time to help researchers gain medical knowledge related to COVID-19.”

São Paulo, Brazil, July 23, 2020:

SOPHiA GENETICS, leader in Data-Driven Medicine, announced today the signature of a Trial Match agreement with Dasa, the largest medical diagnostic company in Latin America. The group chose the SOPHiA Platform to lead the region toward an extensive approach to Data-Driven Medicine powered by the world’s first integrated multimodal solution to fight cancer.

Thanks to a huge community of more than 1’000 partner institutions globally - with almost 100 in Latin America - SOPHiA GENETICS is uniquely positioned to offer new solutions for clinical trials. Through SOPHiA Trial Match, the company will help Dasa facilitate and accelerate the process of biomarker-defined patient recruitment for clinical trials, especially when eligibility criteria include the presence of rare genetic variants. Dasa’s newly integrated network of hospitals, Ímpar, will directly benefit from SOPHiA Trial Match, being able to engage with peers, sharing knowledge, and collaborating with other experts of the SOPHiA global network.

Dasa already adopted the SOPHiA Platform for accurate analysis of genomic profiles back in 2016 through their genomic laboratory GeneOne to detect hereditary and hematologic disorders. Today, with the help of SOPHiA, the number of genomic analyses Dasa performs grows exponentially, including applications in various areas of oncology.

In addition, SOPHiA is also empowering Dasa’s experts with radiomics capabilities, which will allow radiologists and oncologists to make more data-driven informed decisions and enable individualized longitudinal follow-up of patients throughout their disease evolution. SOPHiA’s multimodal solution – including genomics, radiomics, and now the SOPHiA Trial Match - will allow the pharmaceutical industry to explore biomarker identification for cancer.

 “The adoption of SOPHiA Trial Match in the region demonstrates once again Dasa’s commitment to help cancer patients with the most advanced technologies currently available on the market,” said Philippe Menu, Chief Medical Officer at SOPHiA GENETICS. “It will allow us to transform the way we can match patients to the right clinical trial and predict who will benefit the most from targeted therapies and why, revolutionizing drug development, and ultimately leading healthcare toward a new era of democratized Data-Driven Medicine.”

“SOPHiA has become our partner of choice for Data-Driven Medicine as we help deliver transformative progress for patients thanks to the multimodal data approach here in Latin America, first by integrating radiomics and now clinical trials” commented Gustavo Campana, Medical Director of Dasa. “Engaging in Trial Match will help clinicians from Dasa understand better how to follow up, treat and orientate patients towards a more personalized medicine”.

Lausanne, Switzerland, and Boston, United States, April 8, 2020: SOPHiA GENETICS, leader in Data-Driven Medicine, announced today that Lara Hashimoto has joined its Executive Team as Chief Business Officer, effective April 1^st. She will be responsible for Marketing, Product Management and Business Development.

Lara Hashimoto joined the healthcare industry 20 years ago holding several leadership roles spanning Pharma clinical drug development, sales and marketing before moving to  Roche Diagnostics. Here, she held a number of roles responsible for IVD development and commercialization, including the launch of the Oncology companion diagnostics portfolio. Her most recent position before joining SOPHiA GENETICS was Chief Commercial Officer for Roche Sequencing Solutions.

“Lara is a stellar addition to our successful team. She shares the company’s vision regarding multi-modal data approaches and the optimization of drug development and has made it her mission to help improve patients’ lives. Lara will greatly further our efforts to democratize Data-Driven Medicine worldwide,” said Jurgi Camblong, Founder and CEO of SOPHiA GENETICS.

“I believe the future in healthcare will be increasingly individualized with significantly improved outcomes through the application of multi-modality prediction modelling,” said Hashimoto. “SOPHiA GENETICS is best positioned to drive this transformation.”

Lausanne, Switzerland, and Boston, United States, March 26, 2020: SOPHiA GENETICS, leader in Data-Driven Medicine, today announced that it is entering the fight against the COVID-19 coronavirus by extending its partnership with Paragon Genomics, who developed a next-generation sequencing (NGS) assay and leveraging the SOPHiA Platform analytical capabilities, as well as delivering the benefits of this solution to its install base of over 1,000 hospitals worldwide in the next weeks.

The new distinctive solution combines Paragon Genomics’ CleanPlex SARS-CoV-2 NGS panel reagent kit for whole-genome sequencing of the coronavirus with the advanced analytical power of the SOPHiA Platform for a comprehensive solution to fight the COVID-19 pandemic. Through SOPHiA GENETICS global decentralized approach, healthcare institutions worldwide will be able to leverage high quality NGS-based genomic testing in order to scale accurate diagnoses and help address the exponentially growing number of cases.

“This unique solution provides multiple benefits for patients and the global medical community at large: a significant increase in the throughput of available COVID-19 diagnostic tests by complementing current PCR-based approaches, a higher analytical quality notably linked to higher sensitivity, and the ability to longitudinally track the evolution of the virus over time at a whole-genome level. Viral antigenic drifts over time and around the world will be of paramount importance going forward. This will enable us to accelerate accurate diagnosis capabilities, support global epidemiology efforts as the disease progresses and work with our biopharma partners to accelerate the development of candidate vaccines and anti-viral therapeutic approaches,” said SOPHiA GENETICS Chief Medical Officer Philippe Menu.

Jurgi Camblong, Founder and CEO of SOPHiA GENETICS, added, “The current situation is dramatic and diagnostic capabilities haven’t scaled as we would have hoped. NGS approaches seem to become essential. Given that thousands of hospitals around the world are already equipped with NGS instruments, accurate NGS based tests could be critical to scale and support the increasing need for diagnosis. Such approach will require specific data analytics solutions. Given our current install base with SOPHiA Platform in over 1’000 hospitals worldwide we have taken the decision to temporarily deviate our development efforts from our focus on Hereditary disorders and Oncology and add additional resources to support the medical community addressing the current COVID-19 pandemic. Each of those 1,000 hospitals implementing this solution at full capacity could support the diagnostic of over 1,000,000 additional cases per week.”

SAN JOSE, CA, Feb. 27, 2020 – MGI, part of the global genomics leader BGI Group, announced an agreement with SOPHiA GENETICS to provide MGI’s customers access to the SOPHiA Platform for data analysis and interpretation. By combining MGI’s DNBSEQ™ sequencing technology with SOPHiA’s Platform, MGI provides an effective solution for clinical researchers and further drives adoption of MGI’s genetic sequencers.

Under the terms of the non-exclusive agreement, MGI’s customers will have the ability to utilize SOPHiA to convert various assays already validated in the past onto DNBSEQ™ based sequencers. The SOPHiA Platform supports more than 250 genomic applications and over 1,000 healthcare institutions around the world.

 “MGI recognizes that analysis and interpretation of MPS data present challenges to researchers and clinicians, so we are excited to offer the bundled solution of our DNBSEQ™ sequencers with the sophisticated SOPHiA Platform. Our DNBSEQ™and CoolMPS technologies are not only highly accurate, affordable and sensitive, but also very versatile and easy to adapt to any existing library preparation methodologies. This will enable existing MPS users to use MGI DNBSEQ™ sequencers to advance their research and translational genomic goals,” said Dr. Hui Jiang, COO of MGI.

MGI customers will also benefit from the SOPHiA Set-Up Program to start up new assays or transfer their existing assays into DNBSEQ sequencing platforms. The program is designed to support the implementation of MPS-based testing for somatic and germline assays. The Set-Up Program is a robust process that establishes and demonstrates the analytical performance of a genomic application to save time, money and resources that can ultimately be translated to better patient care.

“We are proud that MGI is working with SOPHiA GENETICS to provide their customers with our universal platform to analyze genomic data produced from its sequencers,” said Kevin Puylaert, VP of Business Development at SOPHiA GENETICS. “This further supports essential access to highly accurate data that healthcare institutions require for reliable testing results. This is an additional effort on our mission to continuously democratize Data-Driven Medicine around the world.”

For more information, please visit https://en.mgitech.cn/ and www.SOPHiAGENETICS.com.  

SOUTH SAN FRANCISCO, CA, Feb. 26, 2020 - Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, today announced a collaboration with SOPHiA GENETICS, leader in Data-Driven Medicine to bring access to the universal SOPHiA Platform for advanced genomic analysis to Twist’s customers, providing the analysis and interpretation of sequencing information. Together, the technologies will allow a customer to go from sample to interpretation of the results quickly and efficiently.

Sequencing the whole genome is expensive and often does not provide the depth of information needed for individual genes and the role they play in complex diseases. Target enrichment enables genomic sequencing efforts to be focused in specific regions of interest, which reduces cost and analysis time. Genomic solutions that combine Twist NGS enrichment solutions along with the SOPHiA AI-powered Platform for advanced DNA analysis are designed to support the implementation of NGS application for somatic and germline testing.

“SOPHiA’s mission is to democratize access to Data-Driven Medicine all around the world.With the addition of SOPHiA’s technology to Twist’s advanced products, clinical researchers will benefit from end-to-end, highly-accurate and reliable genomic solutions,” commented Jurgi Camblong CEO and Co-founder of SOPHiA GENETICS. “The combined solution will ultimately help experts precisely detect and characterize genomic mutations and use that information to improve outcomes.”

“Genomics research is enabling a shift from broad-based “one-size-fits-all” approach to a personalized experience,” commented Emily M. Leproust, Ph.D., CEO and co-founder of Twist. “Pairing our industry-leading, rapidly customizable enrichment efficiency with SOPHiA’s robust analytical platform provides customers an important solution to achieve clinically actionable data while saving on sequencing costs. We are excited to work with SOPHiA to provide this new combined offering to clinical researchers around the world.”

For more information, please visit www.twistbioscience.com and www.SOPHiAGENETICS.com.

Lausanne, Switzerland, and Boston, United States – February 20, 2020: SOPHiA GENETICS, leader in Data-Driven Medicine, announced today that former Foundation Medicine CEO Troy Cox has been elected as Chairman of the Board of Directors, effective March 1, 2020. He is replacing Antoine Duchateau, who has served as chairman since 2013 and will continue as a board member. Cox joined the company in July of 2019 as a member of the board.

“This announcement signals how much of an asset Troy has been for SOPHiA GENETICS in this short amount of time,” said Jurgi Camblong, CEO and Co-founder. “I am delighted that he will assume the chairmanship of the company’s board, as his impressive expertise will help us to further expand our community of partners and the scope of new clinical-grade applications to further the success of our mission. I am deeply grateful to Antoine Duchateau for his outstanding guidance over the past 6 years as Chairman of the Board of Directors. His experience has been extremely valuable in driving SOPHiA GENETICS to its current position.”

Recent technological advances help SOPHiA GENETICS leverage even more multi-modal data, ultimately leading SOPHiA into a new era in healthcare. Fast and accurate diagnostics, personalized treatment options, longitudinal patient monitoring and drug development optimization are the concrete benefits of Data-Driven Medicine. This idea has shaped Troy Cox’s entire career, and his election as Chairman of the Board is a direct testimony thereof.

A healthcare industry visionary leader, Troy Cox formerly served as CEO of Foundation Medicine (FMI), where his work was recognized by the acquisition of the company by Roche in 2018. Prior to FMI, he led US BioOncology for a period of unprecedented growth as Senior Vice President and Officer at Genentech, participating in the launch of nearly half of the products. Earlier on, Mr. Cox held executive and senior positions at numerous healthcare companies including UCB BioPharmaceuticals, Sanofi-Aventis, and Schering-Plough.

“I’m proud to take a leadership role at this important time of expansion and to be part of SOPHiA GENETICS mission. Thanks to its global and universal approach that already benefits more than 1,000 hospital partners, SOPHiA is uniquely positioned to lead and promote an important movement in the entire ecosystem” said Troy Cox. “Together, we democratize Data-Driven Medicine, enabling clinical experts to access the full potential of new-generation health data and positively impact patients’ lives all around the world.”

Lausanne, Switzerland, and Boston, United States – February 13, 2020: 

SOPHiA GENETICS, leader in Data-Driven Medicine, announced today the appointment of Philippe Menu, MD-PhD, MBA, as Chief Medical Officer.

Dr. Philippe Menu brings a unique blend of medical expertise across multiple areas including clinical medicine, fundamental research in molecular biology, and management consulting. He spent the last eight years at McKinsey & Company where he co-led the McKinsey Cancer Center and served dozens of clients in the biopharma sector. Dr. Menu advised global pharmaceutical companies, mid-size players and biotech alike across the entire value chain, with a major focus on innovative therapies and diagnostics in oncology and rare diseases.

“The potential linked to new-generation health data is limitless and it is our goal to continue expanding the scope of new clinical applications for our community of more than 1,000 hospitals across 82 countries,” affirmed Jurgi Camblong, CEO and Co-founder of SOPHiA GENETICS. “Philippe’s background and track record across different sectors of life sciences, including biopharma, will help the execution of new clinical-grade applications. In turn, this will allow the longitudinal monitoring of patients through multi-modal data approaches and the optimization of drug development.”

“It is a privilege to be joining SOPHiA GENETICS as Chief Medical Officer,” said Dr. Menu. “I am incredibly inspired by what the SOPHiA team has already achieved by analyzing half a million patients’ genomic profiles across the world through its unique and growing global network of hospital partners. Looking ahead, I am most impressed by the full potential to positively impact patients' lives that still lies ahead of us through the application of SOPHiA's multi-modal data approach. SOPHiA is uniquely positioned to help deliver transformative progress for patients around the world: we can help discover new biomarkers to develop new therapies, match the right treatment to the right patients in clinical trials as well as in routine clinical care, and follow patients longitudinally through a multi-omics approach to help predict who will most benefit from which therapies and why. I look forward to working closely with our hospital, biopharma and other healthcare ecosystem partners to help accelerate the adoption of Data-Driven Medicine."